6JOI: Crystal structure of PDGFRA T674I in complex with crenolanib by co-crystallization

PDB ID: 6JOIDownload
MMDB ID: 185570
PDB Deposition Date: 2019/3/22
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6JOI: monomeric; determined by author
Molecular Components in 6JOI
Label Count Molecule
Protein (1 molecule)
1
Platelet-derived Growth Factor Receptor Alpha
(Gene symbol: PDGFRA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303