6JEZ: Covalent labeling of rVDR-LBD by turn-on fluorescent probe mediated by conjugate addition and cyclization

PDB ID: 6JEZDownload
MMDB ID: 184003
PDB Deposition Date: 2019/2/7
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 6JEZ: dimeric; determined by software (PISA)
Molecular Components in 6JEZ
Label Count Molecule
Proteins (2 molecules)
1
Vitamin D3 Receptor,vitamin D3 Receptor
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 1
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2- methylenecyclohexane-1,3-diol(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2- methylenecyclohexane-1,3-diol
2
1
7-(diethylamino)chromen-2-one7-(diethylamino)chromen-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303