6J5L: Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e

PDB ID: 6J5LDownload
MMDB ID: 177450
PDB Deposition Date: 2019/1/11
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 6J5L: monomeric; determined by author
Molecular Components in 6J5L
Label Count Molecule
Protein (1 molecule)
1
High Affinity Nerve Growth Factor Receptor
(Gene symbol: NTRK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamideN-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303