6ITV: Crystal structure of activated c-KIT in complex with compound

PDB ID: 6ITVDownload
MMDB ID: 181662
PDB Deposition Date: 2018/11/26
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.881  Å
Source Organism:
Similar Structures:
Biological Unit for 6ITV: dimeric; determined by author and by software (PISA)
Molecular Components in 6ITV
Label Count Molecule
Proteins (2 molecules)
2
Mast/stem Cell Growth Factor Receptor KIT
(Gene symbol: KIT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-(5-ethyl-1,2-oxazol-3-yl)-N'-[4-(2-{[6-(4-ethylpyrazin-1(4H)-yl)pyrimidin-4-yl]amino}-1,3-thiazol-5-yl)phenyl]ureaN-(5-ethyl-1,2-oxazol-3-yl)-N'-[4-(2-{[6-(4-ethylpyrazin-1(4H)-yl)pyrimidin-4-yl]amino}-1,3-thiazol-5-yl)phenyl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303