6ISH: Structure of 9N-I DNA polymerase incorporation with 3'-AL in the active site

PDB ID: 6ISHDownload
MMDB ID: 178860
PDB Deposition Date: 2018/11/16
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Thermococcus sp. 9oN-7▼
Similar Structures:
Biological Unit for 6ISH: trimeric; determined by author and by software (PISA)
Molecular Components in 6ISH
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*gp*cp*gp*gp*ap*cp*tp*gp*cp*tp*tp*ap*cp*cp*(dal))-3')
Molecule annotation
1
DNA (5'-d(*ap*cp*tp*gp*gp*tp*ap*ap*gp*cp*ap*gp*tp*cp*cp*gp*c)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
PYROPHOSPHATEPYROPHOSPHATE
2
2
CALCIUM IONCALCIUM ION
3
1
[(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(phosphonooxymethyl)oxolan-3-yl] 3-(2-ethoxyethoxy)propanoate[(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(phosphonooxymethyl)oxolan-3-yl] 3-(2-ethoxyethoxy)propanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303