6IND: Crystal structure of PDE4D complexed with a novel inhibitor

PDB ID: 6INDDownload
MMDB ID: 180636
PDB Deposition Date: 2018/10/24
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.872  Å
Source Organism:
Similar Structures:
Biological Unit for 6IND: dimeric; determined by author and by software (PISA)
Molecular Components in 6IND
Label Count Molecule
Proteins (2 molecules)
2
Camp-specific 3',5'-cyclic Phosphodiesterase 4D
(Gene symbol: PDE4D)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
(1S)-6,7-dimethoxy-1-[2-(6-methyl-1H-indol-3-yl)ethyl]-3,4-dihydroisoquinoline-2(1H)-carbaldehyde(1S)-6,7-dimethoxy-1-[2-(6-methyl-1H-indol-3-yl)ethyl]-3,4-dihydroisoquinoline-2(1H)-carbaldehyde
2
3
MAGNESIUM IONMAGNESIUM ION
3
2
ZINC IONZINC ION
4
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303