6IN3: Crystal structure of DOT1L in complex with 18-Crown-6

PDB ID: 6IN3Download
MMDB ID: 180822
PDB Deposition Date: 2018/10/24
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 6IN3: monomeric; determined by author and by software (PISA)
Molecular Components in 6IN3
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase, H3 Lysine-79 Specific
(Gene symbol: DOT1L)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
3
5
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303