6IN1: Crystal structure of the first bromodomain of BRD4 in complex with 18-Crown-6

PDB ID: 6IN1Download
MMDB ID: 180820
PDB Deposition Date: 2018/10/24
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6IN1: monomeric; determined by author and by software (PISA)
Molecular Components in 6IN1
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamideN-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide
2
1
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE
3
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303