6IBO: Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

PDB ID: 6IBODownload
MMDB ID: 177656
PDB Deposition Date: 2018/11/30
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 2.17  Å
Source Organism:
Similar Structures:
Biological Unit for 6IBO: dimeric; determined by author and by software (PISA)
Molecular Components in 6IBO
Label Count Molecule
Proteins (2 molecules)
1
Udp-n-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 KDA Subunit
(Gene symbol: OGT)
Molecule annotation
1
Ala-val-ser-arg-ala
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate(2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
2
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303