6IBM: Crystal structure of human alpha-galactosidase A in complex with alpha-galactose configured cyclosulfate ME776

PDB ID: 6IBMDownload
MMDB ID: 180248
PDB Deposition Date: 2018/11/30
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.07  Å
Source Organism:
Similar Structures:
Biological Unit for 6IBM: dimeric; determined by author and by software (PISA)
Molecular Components in 6IBM
Label Count Molecule
Proteins (2 molecules)
2
Alpha-galactosidase a
(Gene symbol: GLA)
Molecule annotation
Chemicals and Non-standard biopolymers (51 molecules)
1
12
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
2
4
BETA-D-MANNOSEBETA-D-MANNOSE
3
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
4
ACETATE IONACETATE ION
5
6
SULFATE IONSULFATE ION
6
2
[(1~{S},2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-3,4,5,6-tetrakis(oxidanyl)cyclohexyl] hydrogen sulfate[(1~{S},2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-3,4,5,6-tetrakis(oxidanyl)cyclohexyl] hydrogen sulfate
7
18
1,2-ETHANEDIOL1,2-ETHANEDIOL
8
3
ALPHA-D-MANNOSEALPHA-D-MANNOSE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303