6I4R: Crystal structure of the disease-causing R460G mutant of the human dihydrolipoamide dehydrogenase at 1.44 Angstrom resolution

PDB ID: 6I4RDownload
MMDB ID: 181412
PDB Deposition Date: 2018/11/10
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.439  Å
Source Organism:
Similar Structures:
Biological Unit for 6I4R: dimeric; determined by author and by software (PISA)
Molecular Components in 6I4R
Label Count Molecule
Proteins (2 molecules)
2
Dihydrolipoyl Dehydrogenase, Mitochondrial
(Gene symbol: DLD)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
9
SULFATE IONSULFATE ION
3
2
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303