6HK7: Crystal structure of GSK-3B in complex with pyrazine inhibitor C50

PDB ID: 6HK7Download
MMDB ID: 177436
PDB Deposition Date: 2018/9/5
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6HK7: monomeric; determined by software (PISA)
Molecular Components in 6HK7
Label Count Molecule
Protein (1 molecule)
1
Glycogen Synthase Kinase-3 Beta
(Gene symbol: GSK3B)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GLYCEROLGLYCEROL
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
3-azanyl-~{N}-(2-methoxyethyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide3-azanyl-~{N}-(2-methoxyethyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303