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6HK3:
Crystal structure of GSK-3B in complex with pyrazine inhibitor C44
PDB ID:
6HK3
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MMDB ID:
177434
PDB Deposition Date:
2018/9/5
Updated in MMDB:
2024/10
Experimental Method:
x-ray diffraction
Resolution:
2.35 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6HK3: monomeric; determined by software (PISA)
Molecular Components in 6HK3
Label
Count
Molecule
Protein (1 molecule)
A
1
Glycogen Synthase Kinase-3 Beta
(Gene symbol:
GSK3B
)
Chemicals and Non-standard biopolymers (7 molecules)
1
1
3-azanyl-~{N}-(2-methoxyphenyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide
2
1
MALONATE ION
3
3
GLYCEROL
4
1
CHLORIDE ION
5
1
DIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303