6HBY: HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope

PDB ID: 6HBYDownload
MMDB ID: 178422
PDB Deposition Date: 2018/8/13
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 6HBY: hexameric; determined by author
Molecular Components in 6HBY
Label Count Molecule
Proteins (6 molecules)
1
HLA Class II Histocompatibility Antigen, DR Alpha Chain
(Gene symbol: HLA-DRA)
Molecule annotation
2
HLA Class II Histocompatibility Antigen, Drb1-1 Beta Chain
(Gene symbol: HLA-DRB1)
Molecule annotation
2
Arrpplaelaalnlsgsrl 5T4 Tumour Epitope
Molecule annotation
1
HLA Class II Histocompatibility Antigen, DR Alpha Chain
(Gene symbol: HLA-DRA)
Molecule annotation
Chemicals and Non-standard biopolymers (30 molecules)
1
25
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
5
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303