6H59: Crystal structure of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PgsA1) with CDP-DAG bound

PDB ID: 6H59Download
MMDB ID: 175369
PDB Deposition Date: 2018/7/24
Updated in MMDB: 2019/06
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6H59: dimeric; determined by author and by software (PISA)
Molecular Components in 6H59
Label Count Molecule
Proteins (2 molecules)
2
Cdp-diacylglycerol--inositol 3-phosphatidyltransferase
(Gene symbol: pgsA1)
Molecule annotation
Chemicals and Non-standard biopolymers (32 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
10
SULFATE IONSULFATE ION
3
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
4
2
[(2~{S})-3-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-azanyl-2-oxidanylidene-1,4-dihydropyrimidin-3-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-2-hexanoyloxy-propyl] hexanoate[(2~{S})-3-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-azanyl-2-oxidanylidene-1,4-dihydropyrimidin-3-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-2-hexanoyloxy-propyl] hexanoate
5
14
(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
6
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303