6GXQ: Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1335

PDB ID: 6GXQDownload
MMDB ID: 177241
PDB Deposition Date: 2018/6/27
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 6GXQ: monomeric; determined by author and by software (PISA)
Molecular Components in 6GXQ
Label Count Molecule
Protein (1 molecule)
1
Phosphodiesterase
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
ZINC IONZINC ION
3
3
GUANIDINEGUANIDINE
4
1
3-[5-[(4aR,8aS)-4-OXIDANYLIDENE-3-PROPAN-2-YL-4a,5,8,8a-TETRAHYDROPHTHALAZIN-1-YL]-2-METHOXY-PHENYL]-N-(PHENYLMETHYL)PROP-2-YNAMIDE3-[5-[(4aR,8aS)-4-OXIDANYLIDENE-3-PROPAN-2-YL-4a,5,8,8a-TETRAHYDROPHTHALAZIN-1-YL]-2-METHOXY-PHENYL]-N-(PHENYLMETHYL)PROP-2-YNAMIDE
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303