6GWE: Crystal structure of Thrombin bound to P2 macrocycle

PDB ID: 6GWEDownload
MMDB ID: 206446
PDB Deposition Date: 2018/6/23
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 6GWE: dimeric; determined by author and by software (PISA)
Molecular Components in 6GWE
Label Count Molecule
Proteins (2 molecules)
1
Thrombin Heavy Chain
(Gene symbol: F2)
Molecule annotation
1
Thrombin Light Chain
(Gene symbol: F2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(10S,14S,17R)-14-(3-carbamimidamidopropyl)-3-[[2-(hydroxymethyl)phenyl]methyl]-5,12,15-tris(oxidanylidene)-19-thia-3,6,13,16-tetrazatricyclo[19.4.0.0^{6,10}]pentacosa-1(21),22,24-triene-17-carboxamide(10S,14S,17R)-14-(3-carbamimidamidopropyl)-3-[[2-(hydroxymethyl)phenyl]methyl]-5,12,15-tris(oxidanylidene)-19-thia-3,6,13,16-tetrazatricyclo[19.4.0.0^{6,10}]pentacosa-1(21),22,24-triene-17-carboxamide
2
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303