6GVX: Crystal structure of Maternal Embryonic Leucine Zipper Kinase (MELK) in complex with dorsomorphin (Compound C)

PDB ID: 6GVXDownload
MMDB ID: 175785
PDB Deposition Date: 2018/6/21
Updated in MMDB: 2019/07
Experimental Method:
x-ray diffraction
Resolution: 2.24  Å
Source Organism:
Similar Structures:
Biological Unit for 6GVX: monomeric; determined by author
Molecular Components in 6GVX
Label Count Molecule
Protein (1 molecule)
1
Maternal Embryonic Leucine Zipper Kinase
(Gene symbol: MELK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303