6EIX: Crystal structure of the kinase domain of the Q207E mutant of ACVR1 (ALK2) in complex with a 2-aminopyridine inhibitor K02288

PDB ID: 6EIXDownload
MMDB ID: 154875
PDB Deposition Date: 2017/9/19
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 6EIX: monomeric; determined by software (PISA)
Molecular Components in 6EIX
Label Count Molecule
Protein (1 molecule)
1
Activin Receptor Type-1
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol
2
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303