6ECL: Crystal Structure of a 1,2,4-Triazole Allosteric RNase H Inhibitor in Complex with HIV Reverse Transcriptase

PDB ID: 6ECLDownload
MMDB ID: 178607
PDB Deposition Date: 2018/8/8
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.385  Å
Source Organism:
Similar Structures:
Biological Unit for 6ECL: dimeric; determined by author and by software (PISA)
Molecular Components in 6ECL
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
MANGANESE (II) IONMANGANESE (II) ION
2
1
1-[4-methoxy-3-[[5-methyl-4-(phenylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]ethanone1-[4-methoxy-3-[[5-methyl-4-(phenylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]ethanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303