6E37: O-GlcNAc Transferase in complex with covalent inhibitor

PDB ID: 6E37Download
MMDB ID: 180960
PDB Deposition Date: 2018/7/13
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 2.531  Å
Source Organism:
Similar Structures:
Biological Unit for 6E37: dimeric; determined by author and by software (PISA)
Molecular Components in 6E37
Label Count Molecule
Proteins (2 molecules)
1
O-glcnac Transferase Subunit P110
(Gene symbol: OGT)
Molecule annotation
1
Tyr-pro-gly-gly-ser-thr-pro-val-ser-ser-ala-asn
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S,3R,4R,5S,6R)-3-[(2E)-but-2-enoylamino]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)(2S,3R,4R,5S,6R)-3-[(2E)-but-2-enoylamino]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303