6E1A: Menin bound to M-89

PDB ID: 6E1ADownload
MMDB ID: 177226
PDB Deposition Date: 2018/7/9
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6E1A: monomeric; determined by author and by software (PISA)
Molecular Components in 6E1A
Label Count Molecule
Protein (1 molecule)
1
Menin
(Gene symbol: MEN1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(1S,2R)-2-[(4S)-2-methyl-4-{1-[(1-{4-[(pyridin-4-yl)sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}-1,2,3,4-tetrahydroisoquinolin-4-yl]cyclopentyl methylcarbamate(1S,2R)-2-[(4S)-2-methyl-4-{1-[(1-{4-[(pyridin-4-yl)sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}-1,2,3,4-tetrahydroisoquinolin-4-yl]cyclopentyl methylcarbamate
2
5
praseodymium triacetatepraseodymium triacetate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303