6E0I: Crystal structure of Glucokinase in complex with compound 72

PDB ID: 6E0IDownload
MMDB ID: 177224
PDB Deposition Date: 2018/7/6
Updated in MMDB: 2019/07
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 6E0I: monomeric; determined by author and by software (PISA)
Molecular Components in 6E0I
Label Count Molecule
Protein (1 molecule)
1
Glucokinase
(Gene symbol: GCK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
1-{4-[5-({3-[(2-methylpyridin-3-yl)oxy]-5-[(pyridin-2-yl)sulfanyl]pyridin-2-yl}amino)-1,2,4-thiadiazol-3-yl]piperidin-1 -yl}ethan-1-one1-{4-[5-({3-[(2-methylpyridin-3-yl)oxy]-5-[(pyridin-2-yl)sulfanyl]pyridin-2-yl}amino)-1,2,4-thiadiazol-3-yl]piperidin-1 -yl}ethan-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303