6DZZ: Cryo-EM Structure of the wild-type human serotonin transporter in complex with ibogaine and 15B8 Fab in the inward conformation

PDB ID: 6DZZDownload
MMDB ID: 174543
PDB Deposition Date: 2018/7/5
Updated in MMDB: 2019/11
Experimental Method:
electron microscopy
Resolution: 3.6  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 6DZZ: trimeric; determined by author
Molecular Components in 6DZZ
Label Count Molecule
Proteins (3 molecules)
1
Sodium-dependent Serotonin Transporter
Molecule annotation
1
15b8 Antibody Heavy Chain
Molecule annotation
1
15b8 Antibody Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(5beta)-12-methoxyibogamine(5beta)-12-methoxyibogamine
2
2
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
3
1
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303