6DUC: Crystal structure of mutant beta-K167T tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid (1D0) at t

PDB ID: 6DUCDownload
MMDB ID: 176681
PDB Deposition Date: 2018/6/20
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.791  Å
Source Organism:
Similar Structures:
Biological Unit for 6DUC: tetrameric; determined by author and by software (PISA)
Molecular Components in 6DUC
Label Count Molecule
Proteins (4 molecules)
2
Tryptophan Synthase Alpha Chain
Molecule annotation
2
Tryptophan Synthase Beta Chain
Molecule annotation
Chemicals and Non-standard biopolymers (47 molecules)
1
2
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE
2
12
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
18
CHLORIDE IONCHLORIDE ION
5
2
(2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-3-[(2-hydroxyphenyl)amino]propanoic acid(2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-3-[(2-hydroxyphenyl)amino]propanoic acid
6
2
2-AMINOPYRIDINE2-AMINOPYRIDINE
7
5
CESIUM IONCESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303