6DN0: Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D

PDB ID: 6DN0Download
MMDB ID: 176005
PDB Deposition Date: 2018/6/5
Updated in MMDB: 2019/06
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6DN0: dimeric; determined by author and by software (PISA)
Molecular Components in 6DN0
Label Count Molecule
Proteins (2 molecules)
1
Human Variable Heavy Chain of Herceptin Containing VH Mutation K30d
Molecule annotation
1
Human Variable Light Chain of Herceptin Containing VL Mutation S52d
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303