6DBC: Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue

PDB ID: 6DBCDownload
MMDB ID: 181193
PDB Deposition Date: 2018/5/3
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 1.05  Å
Source Organism:
Similar Structures:
Biological Unit for 6DBC: monomeric; determined by author and by software (PISA)
Molecular Components in 6DBC
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 2
(Gene symbol: BRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303