6CM2: SAMHD1 HD domain bound to decitabine triphosphate

PDB ID: 6CM2Download
MMDB ID: 176447
PDB Deposition Date: 2018/3/2
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.14  Å
Source Organism:
Similar Structures:
Biological Unit for 6CM2: tetrameric; determined by author and by software (PISA)
Molecular Components in 6CM2
Label Count Molecule
Proteins (4 molecules)
4
Deoxynucleoside Triphosphate Triphosphohydrolase Samhd1
(Gene symbol: SAMHD1)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
8
6-amino-3-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-3,4-dihydro-1,3,5-triazin-2(1H)-one6-amino-3-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-3,4-dihydro-1,3,5-triazin-2(1H)-one
2
4
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
3
4
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303