6AWQ: Anomalous chloride signal reveals the position of sertraline complexed with the serotonin transporter at the central site

PDB ID: 6AWQDownload
MMDB ID: 155465
PDB Deposition Date: 2017/9/6
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 4.046  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 6AWQ: trimeric; determined by author and by software (PISA)
Molecular Components in 6AWQ
Label Count Molecule
Proteins (3 molecules)
1
Sodium-dependent Serotonin Transporter
Molecule annotation
1
8B6 Antibody FAB Heavy Chain
Molecule annotation
1
8B6 Antibody FAB Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
2
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
CHOLESTEROLCHOLESTEROL
4
1
CHLORIDE IONCHLORIDE ION
5
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303