6AQJ: Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity

PDB ID: 6AQJDownload
MMDB ID: 155217
PDB Deposition Date: 2017/8/20
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.373  Å
Source Organism:
Similar Structures:
Biological Unit for 6AQJ: dimeric; determined by author and by software (PISA)
Molecular Components in 6AQJ
Label Count Molecule
Proteins (2 molecules)
2
Ketol-acid Reductoisomerase (Nadp(+))
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
oxo(propan-2-ylamino)acetic acidoxo(propan-2-ylamino)acetic acid
3
4
GLYCEROLGLYCEROL
4
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
5
2
N-HYDROXY-N-ISOPROPYLOXAMIC ACIDN-HYDROXY-N-ISOPROPYLOXAMIC ACID
6
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303