5XTB: Cryo-EM structure of human respiratory complex I matrix arm

PDB ID: 5XTBDownload
MMDB ID: 154182
PDB Deposition Date: 2017/6/18
Updated in MMDB: 2017/12
Experimental Method:
electron microscopy
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 5XTB: octadecameric; determined by author
Molecular Components in 5XTB
Label Count Molecule
Proteins (18 molecules)
1
Nadh Dehydrogenase [ubiquinone] Flavoprotein 1, Mitochondrial
(Gene symbol: NDUFV1)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 8, Mitochondrial
(Gene symbol: NDUFS8)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 7, Mitochondrial
(Gene symbol: NDUFS7)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 6
(Gene symbol: NDUFA6)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 2
(Gene symbol: NDUFA2)
Molecule annotation
1
Acyl Carrier Protein, Mitochondrial
(Gene symbol: NDUFAB1)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 5
(Gene symbol: NDUFA5)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 7
(Gene symbol: NDUFA7)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 9, Mitochondrial
(Gene symbol: NDUFA9)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Flavoprotein 3, Mitochondrial
(Gene symbol: NDUFV3)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 4, Mitochondrial
(Gene symbol: NDUFS4)
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase 75 KDA Subunit, Mitochondrial
(Gene symbol: NDUFS1)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 12
(Gene symbol: NDUFA12)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Flavoprotein 2, Mitochondrial
(Gene symbol: NDUFV2)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 3, Mitochondrial
(Gene symbol: NDUFS3)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 2, Mitochondrial
(Gene symbol: NDUFS2)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 6, Mitochondrial
(Gene symbol: NDUFS6)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 13
(Gene symbol: NDUFA13)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
6
IRON/SULFUR CLUSTERIRON/SULFUR CLUSTER
2
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
3
1
S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioateS-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate
4
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
5
2
FE2/S2 (INORGANIC) CLUSTERFE2/S2 (INORGANIC) CLUSTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303