5XR8: Crystal structure of the human CB1 in complex with agonist AM841

PDB ID: 5XR8Download
MMDB ID: 152759
PDB Deposition Date: 2017/6/7
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5XR8: monomeric; determined by software (PISA)
Molecular Components in 5XR8
Label Count Molecule
Protein (1 molecule)
1
Cannabinoid Receptor 1,flavodoxin,cannabinoid Receptor 1
(Gene symbol: DVU2680)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
2
1
(6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol(6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol
3
1
CHOLESTEROLCHOLESTEROL
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303