5XLT: The crystal structure of tubulin in complex with 4'-demethylepipodophyllotoxin

PDB ID: 5XLTDownload
MMDB ID: 154851
PDB Deposition Date: 2017/5/11
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.813  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 5XLT: hexameric; determined by author
Molecular Components in 5XLT
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Tubulin Tyrosine Ligase
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
4
MAGNESIUM IONMAGNESIUM ION
3
2
CALCIUM IONCALCIUM ION
4
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
5
2
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
6
2
(5S,5aR,8aR,9R)-9-(3,5-dimethoxy-4-oxidanyl-phenyl)-5-oxidanyl-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one(5S,5aR,8aR,9R)-9-(3,5-dimethoxy-4-oxidanyl-phenyl)-5-oxidanyl-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
7
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303