5XKM: Crystal structure of human phosphodiesterase 2A in complex with 6-methyl-N-(1-(4-(trifluoromethoxy)phenyl)propyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

PDB ID: 5XKMDownload
MMDB ID: 153805
PDB Deposition Date: 2017/5/8
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.16  Å
Source Organism:
Similar Structures:
Biological Unit for 5XKM: dimeric; determined by author and by software (PISA)
Molecular Components in 5XKM
Label Count Molecule
Proteins (2 molecules)
2
Cgmp-dependent 3',5'-cyclic Phosphodiesterase
(Gene symbol: PDE2A)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
MAGNESIUM IONMAGNESIUM ION
2
2
ZINC IONZINC ION
3
2
6-methyl-N-[(1R)-1-[4-(trifluoromethyloxy)phenyl]propyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide6-methyl-N-[(1R)-1-[4-(trifluoromethyloxy)phenyl]propyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303