5X8Q: Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain With rockogenin

PDB ID: 5X8QDownload
MMDB ID: 151637
PDB Deposition Date: 2017/3/3
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5X8Q: dimeric; determined by author and by software (PISA)
Molecular Components in 5X8Q
Label Count Molecule
Proteins (2 molecules)
1
Nuclear Receptor Ror-gamma
(Gene symbol: RORC)
Molecule annotation
1
Nuclear Receptor Corepressor 2
(Gene symbol: NCOR2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(1R,2S,4S,5'R,6R,7S,8R,9S,10R,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-10,16-diol(1R,2S,4S,5'R,6R,7S,8R,9S,10R,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-10,16-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303