5X7D: Structure of beta2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist

PDB ID: 5X7DDownload
MMDB ID: 153793
PDB Deposition Date: 2017/2/25
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 2.703  Å
Source Organism:
Similar Structures:
Biological Unit for 5X7D: monomeric; determined by author and by software (PISA)
Molecular Components in 5X7D
Label Count Molecule
Protein (1 molecule)
1
Chimera Protein of Beta-2 Adrenergic Receptor and Lysozyme
(Gene symbol: ADRB2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
2
2
CHOLESTEROLCHOLESTEROL
3
1
4-carbamoyl-N-[(2R)-2-cyclohexyl-2-phenylacetyl]-L-phenylalanyl-3-bromo-N-methyl-L-phenylalaninamide4-carbamoyl-N-[(2R)-2-cyclohexyl-2-phenylacetyl]-L-phenylalanyl-3-bromo-N-methyl-L-phenylalaninamide
4
1
(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol
5
1
1,4-BUTANEDIOL1,4-BUTANEDIOL
6
1
ACETAMIDEACETAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303