5WUU: Complex structure of the first bromodomain of BRD4 with an inhibitor that containing a 2H-chromen-2-one ring

PDB ID: 5WUUDownload
MMDB ID: 149819
PDB Deposition Date: 2016/12/21
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.724  Å
Source Organism:
Similar Structures:
Biological Unit for 5WUU: monomeric; determined by author
Molecular Components in 5WUU
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-methyl-~{N}-[3-[(2-oxidanylidenechromen-4-yl)amino]propyl]thiophene-2-carboxamide~{N}-methyl-~{N}-[3-[(2-oxidanylidenechromen-4-yl)amino]propyl]thiophene-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303