5WE8: Crystal structure of WNK1 in complex with N-{(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl}-2-(3-methoxyphenyl)-N-methylquinoline-4-carboxamide (compound 8)

PDB ID: 5WE8Download
MMDB ID: 153765
PDB Deposition Date: 2017/7/7
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 2.006  Å
Source Organism:
Similar Structures:
Biological Unit for 5WE8: monomeric; determined by author
Molecular Components in 5WE8
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Wnk1
(Gene symbol: WNK1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
3
2
N-{(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl}-2-(3-methoxyphenyl)-N-methylquinoline-4-carboxamideN-{(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl}-2-(3-methoxyphenyl)-N-methylquinoline-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303