5WB7: Crystal structure of the epidermal growth factor receptor extracellular region in complex with epiregulin

PDB ID: 5WB7Download
MMDB ID: 155175
PDB Deposition Date: 2017/6/28
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.941  Å
Source Organism:
Similar Structures:
Biological Unit for 5WB7: tetrameric; determined by author and by software (PISA)
Molecular Components in 5WB7
Label Count Molecule
Proteins (4 molecules)
2
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
2
Proepiregulin
(Gene symbol: EREG)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
14
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
beta-D-mannopyranosebeta-D-mannopyranose
3
1
alpha-D-mannopyranosealpha-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303