5VSE: Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 17: N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine

PDB ID: 5VSEDownload
MMDB ID: 152888
PDB Deposition Date: 2017/5/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5VSE: monomeric; determined by author
Molecular Components in 5VSE
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Ehmt2
(Gene symbol: EHMT2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
ZINC IONZINC ION
2
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
1
N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamineN~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303