5VSC: Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 13

PDB ID: 5VSCDownload
MMDB ID: 152730
PDB Deposition Date: 2017/5/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 5VSC: dimeric; determined by author and by software (PISA)
Molecular Components in 5VSC
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase Ehmt2
(Gene symbol: EHMT2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
8
ZINC IONZINC ION
2
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
2
6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303