5VGO: Bruton's tyrosine kinase (BTK) with compound G-744

PDB ID: 5VGODownload
MMDB ID: 152498
PDB Deposition Date: 2017/4/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.621  Å
Source Organism:
Similar Structures:
Biological Unit for 5VGO: monomeric; determined by author and by software (PISA)
Molecular Components in 5VGO
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase BTK
(Gene symbol: BTK)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
SULFATE IONSULFATE ION
2
2
GLYCEROLGLYCEROL
3
2
2-(2-METHOXYETHOXY)ETHANOL2-(2-METHOXYETHOXY)ETHANOL
4
1
2-[2-(hydroxymethyl)-3-{1-methyl-6-oxo-5-[(pyrimidin-4-yl)amino]-1,6-dihydropyridin-3-yl}phenyl]-6,6-dimethyl-3,4,6,7-tetrahydro-2H-cyclopenta[4,5]thieno[2,3-c]pyridin-1(5H)-one2-[2-(hydroxymethyl)-3-{1-methyl-6-oxo-5-[(pyrimidin-4-yl)amino]-1,6-dihydropyridin-3-yl}phenyl]-6,6-dimethyl-3,4,6,7-tetrahydro-2H-cyclopenta[4,5]thieno[2,3-c]pyridin-1(5H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303