5VGI: Crystal Structure of KDM4 with the Small Molecule Inhibitor QC6352

PDB ID: 5VGIDownload
MMDB ID: 154825
PDB Deposition Date: 2017/4/11
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.07  Å
Source Organism:
Similar Structures:
Biological Unit for 5VGI: monomeric; determined by author and by software (PISA)
Molecular Components in 5VGI
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 4A
(Gene symbol: KDM4A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
NICKEL (II) IONNICKEL (II) ION
2
1
ZINC IONZINC ION
3
1
3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303