5VDK: Crystal structure of human WEE2 kinase domain in complex with MK1775

PDB ID: 5VDKDownload
MMDB ID: 153933
PDB Deposition Date: 2017/4/3
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 5VDK: monomeric; determined by author and by software (PISA)
Molecular Components in 5VDK
Label Count Molecule
Protein (1 molecule)
1
Wee1-like Protein Kinase 2
(Gene symbol: WEE2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one
2
3
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303