5VD2: crystal structure of human WEE1 kinase domain in complex with PF-03814735

PDB ID: 5VD2Download
MMDB ID: 153931
PDB Deposition Date: 2017/4/1
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 5VD2: monomeric; determined by author and by software (PISA)
Molecular Components in 5VD2
Label Count Molecule
Protein (1 molecule)
1
Wee1-like Protein Kinase
(Gene symbol: WEE1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-{2-[(1S,4R)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamideN-{2-[(1S,4R)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide
2
1
PHOSPHATE IONPHOSPHATE ION
3
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303