5VCY: CRYSTAL STRUCTURE OF HUMAN MYT1 KINASE DOMAIN IN COMPLEX WITH BOSUTINIB

PDB ID: 5VCYDownload
MMDB ID: 153927
PDB Deposition Date: 2017/4/1
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.56  Å
Source Organism:
Similar Structures:
Biological Unit for 5VCY: monomeric; determined by author and by software (PISA)
Molecular Components in 5VCY
Label Count Molecule
Protein (1 molecule)
1
Membrane-associated Tyrosine- and Threonine-specific Cdc2-inhibitory Kinase
(Gene symbol: PKMYT1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303