5VC6: crystal structure of human WEE1 kinase domain in complex with PHA-848125

PDB ID: 5VC6Download
MMDB ID: 153923
PDB Deposition Date: 2017/3/31
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 5VC6: monomeric; determined by author and by software (PISA)
Molecular Components in 5VC6
Label Count Molecule
Protein (1 molecule)
1
Wee1-like Protein Kinase
(Gene symbol: WEE1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDEN,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303