5VC5: Crystal structure of human WEE1 kinase domain in complex with PD-166285

PDB ID: 5VC5Download
MMDB ID: 153922
PDB Deposition Date: 2017/3/31
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.93  Å
Source Organism:
Similar Structures:
Biological Unit for 5VC5: monomeric; determined by author and by software (PISA)
Molecular Components in 5VC5
Label Count Molecule
Protein (1 molecule)
1
Wee1-like Protein Kinase
(Gene symbol: WEE1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
CHLORIDE IONCHLORIDE ION
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303