5V8O: Discovery of a high affinity inhibitor of cGAS

PDB ID: 5V8ODownload
MMDB ID: 154815
PDB Deposition Date: 2017/3/22
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5V8O: dimeric; determined by author and by software (PISA)
Molecular Components in 5V8O
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
ZINC IONZINC ION
2
3
5-phenyltetrazolo[1,5-a]pyrimidin-7-ol5-phenyltetrazolo[1,5-a]pyrimidin-7-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303