5V7W: Crystal structure of human PARP14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one inhibitor

PDB ID: 5V7WDownload
MMDB ID: 150737
PDB Deposition Date: 2017/3/20
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 5V7W: monomeric; determined by author and by software (PISA)
Molecular Components in 5V7W
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 14
(Gene symbol: PARP14)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303